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Comparison of DNA targeting CRISPR editors in human cells

2022-10-21

Abstract excerpt

Profiling and comparing the performance of current widely used DNA targeting CRISPR systems provide the basic information for the gene-editing toolkit and can be a useful resource for this field. Herein we made a parallel comparison between the recently reported miniature Cas12f1 and the widely used Cas12a and Cas9 nucleases in mammalian cells. The results revealed that as a CRISPRa activator, Un1Cas12f1 could ind...

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Literature Corpus work
1fdad3d5-31fe-57a2-9ed3-e88a70e578ec
DOI
10.1101/2022.10.20.513037
Open publication

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Comparison of DNA targeting CRISPR editors in human cellsDOI 10.1101/2022.10.20.513037
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