Advancements and Obstacles of CRISPR-Cas9 Technology in Translational Research

doi:10.1016/j.omtm.2019.02.008

Article

Advancements and Obstacles of CRISPR-Cas9 Technology in Translational Research

15 Mar 2019

Abstract excerpt

The expanding CRISPR-Cas9 technology is an easily accessible, programmable, and precise gene-editing tool with numerous applications, most notably in biomedical research. Together with advancements in genome and transcriptome sequencing in the era of metadata, genomic engineering with CRISPR-Cas9 meets the developmental requirements of precision medicine, and clinical tests using CRISPR-Cas9 are now possible....

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