Article

Lung Adenocarcinoma Cells Respond Differently to Mechanical Stress in 3D Versus 2D Environments

2025-06-13

Abstract excerpt

<title>Abstract</title> <p> The tumour microenvironment is influenced by mechanical stress, including shear and stretch forces, which regulate cancer cell behaviour. Although two-dimensional (2D) culture models are commonly used in cancer research, they fail to recapitulate complex mechanical cues of native tissues. In this study, we developed an <italic>ex vivo</italic> three-dimensional (3D) lung cancer mode...

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Literature Corpus work: 1fce5efb-562d-5915-be8c-95e8a11a9ec4
DOI: 10.21203/rs.3.rs-6482124/v1

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