Article

Myofibroblasts Derived Type V Collagen Promoting Tissue Mechanical Stress and Facilitating Metastasis and Therapy Resistance of Lung Adenocarcinoma Cells

2024-04-12

Abstract excerpt

<title>Abstract</title> <p>Background Lung cancer accounts for 11.6% of new diagnosed malignancy cases and stands as a major cause of global cancer-related deaths, with a 5-year survival rate of 5% for Lung Adenocarcinoma (LUAD), which is one of the major histology type of lung cancer. Mechanical alterations in the tumor microenvironment, including extracellular matrix (ECM) remodeling and fibroblast activity, l...

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Literature Corpus work: 06e53fbf-64cc-5d4d-b5fb-28510b822c95
DOI: 10.21203/rs.3.rs-4011973/v1

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