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Article

Antiviral roles of interferon regulatory factor (IRF)-1, 3 and 7 against human coronavirus infection

2022-03-27

Abstract excerpt

Interferon regulatory factors (IRFs) are key elements of antiviral innate responses that regulate transcription of interferons (IFNs) and IFN-stimulated genes (ISGs). As many human coronaviruses are known to be sensitive to IFN, antiviral roles of IRFs are yet to be fully understood. TypeI or II IFN treatment protected MRC5 cells from infection of human coronavirus 229E, but not human coronavirus OC43. Infection o...

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Literature Corpus work
1f814e54-7580-5902-a3d0-d4b6b5a8c421
DOI
10.1101/2022.03.24.485591
Open publication

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Antiviral roles of interferon regulatory factor (IRF)-1, 3 and 7 against human coronavirus infectionDOI 10.1101/2022.03.24.485591
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