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Combining A Massively Parallel Reporter Assay and Human Data to Elucidate Genetic Mechanisms Driving Risk for Juvenile Idiopathic Arthritis

2026-08-27

Abstract excerpt

While progress has been made in identifying the true risk-driving single nucleotide polymorphisms (SNPS) on juvenile idiopathic arthritis (JIA) risk haplotypes, the affected cells and target genes largely remain unknown. We used data from a previously published massively parallel reporter assay (MPRA) to query human data in the Database of Immune Cell eQTLs (DICE) and the Gene-Tissue Expression (GTEx) database to...

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Literature Corpus work: 1f5e3955-f2f9-5fcf-a192-543a3bd2f58c
DOI: 10.64898/2026.08.24.26361225

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