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Contribution of Three tRNA Modification Enzymes to <i>Proteus mirabilis</i> Fitness and Catheter-Associated Urinary Tract Infection

2025-12-17

Abstract excerpt

RNA modifications play essential roles in cellular physiology by modulating RNA structure, stability, and translation efficiency. Among these, dihydrouridine is a conserved tRNA modification synthesized by the flavin-dependent enzymes DusA, DusB, and DusC, which introduces flexibility at defined uridine positions in the D-loop. While structural and biochemical studies in Escherichia coli have clarified Dus enzyme...

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Literature Corpus work
1f4d797c-0c27-570d-ba9e-25d1ed3ed17b
DOI
10.64898/2025.12.17.694933
Open publication

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Contribution of Three tRNA Modification Enzymes to <i>Proteus mirabilis</i> Fitness and Catheter-Associated Urinary Tract InfectionDOI 10.64898/2025.12.17.694933
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