Back to search

Article

Pangenome Analysis of <i>Proteus mirabilis</i> Reveals Lineage-Specific Antimicrobial Resistance Profiles and Discordant Genotype-Phenotype Correlations

2025-11-22

Abstract excerpt

<h4>ABSTRACT</h4> Urinary tract infections (UTIs) impose a large healthcare burden, with escalating antimicrobial resistance (AMR) and treatment failure. Proteus mirabilis is an under-characterized and challenging UTI pathogen due to intrinsic resistances and biofilm formation. To understand P. mirabilis population genomics, we combined pangenome analysis, in silico AMR predication, and phenotypic antimicrobia...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
253c44f1-ee67-57bf-984d-8b697ed9af1a
DOI
10.1101/2025.11.21.689858
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Pangenome Analysis of <i>Proteus mirabilis</i> Reveals Lineage-Specific Antimicrobial Resistance Profiles and Discordant Genotype-Phenotype CorrelationsDOI 10.1101/2025.11.21.689858
Pangenome analysis of Proteus mirabilis reveals lineage-specific antimicrobial resistance profiles and discordant genotype-phenotype correlations.Semantic proximity
Proteus mirabilis entails a switch from commensal to pathogen - Genomic insights from a blaTEM-1B-harboring novel isolate from IndiaSemantic proximity
Genomic Constellation of Foodborne Proteus Mirabilis Isolates Harboring AMR, Virulence Genes and Comparative WGS Analysis.Semantic proximity
Genetic analysis of resistance and virulence characteristics of clinical multidrug-resistant Proteus mirabilis isolatesSemantic proximity
A Core Genome Multilocus Sequence Typing Scheme for Proteus mirabilis.Semantic proximity
Genetic landscape of biofilm forming uropathogenic<i>E. coli</i>from clinical samplesSemantic proximity
Investigation of genomic islands involved in antimicrobial resistance in Proteus mirabilis isolated from swine.Semantic proximity
Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environmentSemantic proximity
Keeping up with the pathogens: Improved antimicrobial resistance detection and prediction from<i>Pseudomonas</i>aeruginosa genomesSemantic proximity
Genetics of Acquired Antibiotic Resistance Genes in Proteus spp.Semantic proximity
An Escherichia coli ST131 pangenome atlas reveals population structure and evolution across 4,071 isolates.Semantic proximity
Combining functional and structural genomics to track antibiotic resistance genes in mobile elements in clinical bacterial strainsSemantic proximity
Select a neighboring publication to make it the new centre.