Article

PIEZO1 upregulation in spinal cord astrocytes during MOG <sub>35-55</sub> -induced EAE correlates with ECM remodeling

2026-06-25

Abstract excerpt

<h4>Background</h4> Extracellular matrix (ECM) remodeling is increasingly recognized as an important component of neuroinflammatory pathology in multiple sclerosis (MS), yet the mechanisms by which CNS cells sense and respond to alterations in their mechanical environment and the spatial across which mechanical changes can influence cellular behavior remain poorly understood. Piezo1 is a mechanosensitive ion chan...

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Literature Corpus work: 1f44ebc1-9889-5795-a429-c9c221c2fe40
DOI: 10.64898/2026.06.23.734091

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