Article
The mechanoreceptor PIEZO1 is a novel oncogene in glioma by promoting astrocyte reactivity
2024-04-30
Abstract excerpt
Glioblastoma is the most common and aggressive brain tumour in adults. Despite advances in its molecular characterization, there is a gap-of-knowledge in the identification of bona fide drivers and potential therapeutic targets that could change the clinical picture. Mechanoreception, the sensing of mechanical cues by cells, has proven to be an important factor in cell biology, particularly in cancer. Piezo1 is a...
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Identifiers and source
- Literature Corpus work
- 516789f6-5c61-5c54-ad94-d91751cfa9dd
- DOI
- 10.1101/2024.04.30.591858