Article

Chronic thromboembolic pulmonary vascular disease : physiological concepts and genetic predisposition

2014-01-01

Abstract excerpt

Chronic thromboembolic pulmonary hypertension (CTEPH) is an uncommon sequela of acute pulmonary embolism and, untreated, leads to right ventricular (RV) failure and death. Despite its growing recognition, methods for the detection of early RV insufficiency and prediction of clinical deterioration, important to optimum preservation of RV function, are currently suboptimal. Furthermore, underlying genetic predisposi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1f3c8d1d-8bb3-54c8-96d7-c99c7ae62142
DOI: 10.25560/23287

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Chronic thromboembolic pulmonary vascular disease : physiological concepts and genetic predispositionDOI 10.25560/23287Read

Genetic and Clinical Determinants of Chronic Thromboembolic Pulmonary Hypertension: The Role of PAI-1 Polymorphism.Semantic proximity Read

Do Hemodynamic Definitions of Chronic Thromboembolic Pulmonary Hypertension Distinguish between Distinct Phenotypes of Chronic Thromboembolic Pulmonary Disease?Semantic proximity Read

Molecular Research in Chronic Thromboembolic Pulmonary HypertensionSemantic proximity Read

A genome-wide association study in chronic thromboembolic pulmonary hypertension and the ADAMTS13-VWF axisSemantic proximity Read

Sickle cell disease-associated pulmonary hypertension: an integrated framework linking pathologies, mechanisms, and clinical phenotypes.Semantic proximity Read

Shared and Distinct Genomics of Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Embolism.Semantic proximity Read

Chronic thromboembolism phenotypes after acute pulmonary embolism: identification with the SEARCH algorithm.Semantic proximity Read

Pulmonary arteriovenous malformation risks: Single-centre hybrid study of 1,149 cases re-emphasises hypoxemia without pulmonary hypertension, and paradoxical embolic/infective stroke etiologiesSemantic proximity Read

Targeting pathogenic VWF/ADAMTS13 dysregulation attenuates CTEPH progressionSemantic proximity Read

The role of endothelial cell function in regulating fibrinolysis and the development and progression of thromboembolic pulmonary hypertensionSemantic proximity Read

Fibrinogen Aα Thr312Ala polymorphism specifically contributes to chronic thromboembolic pulmonary hypertension by increasing fibrin resistance.Semantic proximity Read

Pathophysiological basis for anticoagulant and antithrombotic therapy in pulmonary hypertension.Semantic proximity Read