Article

Interleukin-13-mediated alterations in esophageal epithelial mitochondria contribute to tissue remodeling in eosinophilic esophagitis

2025-04-02

Abstract excerpt

<h4>Background</h4> The significance of mitochondria in EoE pathobiology remains elusive. <h4>Objective</h4> To determine the impact of EoE inflammatory mediators upon mitochondrial biology in esophageal epithelium, the mechanisms mediating these effects, and their functional significance to EoE pathobiology. <h4>Methods</h4> Mitochondria were evaluated in human biopsies, MC903/Ovalbumin-induced murine EoE, and...

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Literature Corpus work: 1eb31226-ed7f-5b9f-a2eb-be19735f385d
DOI: 10.1101/2025.04.02.646853

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