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Zika virus modulates arthropod histone methylation for its survival in mosquito cells

13 Feb 2025

Abstract excerpt

Zika virus (ZIKV) is a mosquito-borne human pathogen that causes mild febrile illness in adults and severe neurological complications and microcephaly in newborns. Studies have reported that ZIKV modulates methylation of human and viral RNA critical for its replication in vertebrate cells. In this study, we show that ZIKV modulates mosquito S-adenosyl methionine (SAMe)-synthase, an enzyme involved in the...

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PMID: 39946368
DOI: 10.1371/journal.pone.0319290

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