Article

Neuropsin in Mental Health

2019-05-29

Abstract excerpt

Neuropsin is an extracellular matrix serine protease that governs the proteolytic cleavage of synaptic proteins and consequently synaptic structural plasticity. In the brain, its substrates include the cell adhesion molecules Neuregulin-1 and L1CAM, that have been linked to neurodevelopmental processes and disorders, such as schizophrenia and bipolar disorder. Neuropsin mRNA is abundant in the cerebellum and sever...

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Literature Corpus work: 1e65beb0-113a-5144-9762-86bc21ab57c0
DOI: 10.20944/preprints201905.0360.v1

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