Article

Matrix Metalloproteinase-9 (MMP-9) as a Potential Regulator of Blood–Brain Barrier Dysfunction in Pediatric Acute Neuropsychiatric Syndrome (PANS)

2026-05-07

Abstract excerpt

<title>Abstract</title> <p> Background Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) is characterized by the abrupt onset of obsessive–compulsive symptoms and/or restrictive eating accompanied by disturbances in sleep, affect regulation, behavior, motor function, and sensory processing. Increasing evidence implicates systemic immune activation and circulating autoantibodies in basal ganglia dysfunction...

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Literature Corpus work: 87b533b6-e8d5-59de-8f52-d696fa901b7d
DOI: 10.21203/rs.3.rs-9442808/v1

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