Article

Precise identification of cell states altered in disease with healthy single-cell references

2022-11-10

Abstract excerpt

Single cell genomics is a powerful tool to distinguish altered cell states in disease tissue samples, through joint analysis with healthy reference datasets. Collections of data from healthy individuals are being integrated in cell atlases that provide a comprehensive view of cellular phenotypes in a tissue. However, it remains unclear whether atlas datasets are suitable references for disease-state identification...

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Literature Corpus work: 1e592446-4851-5da5-bff3-3d8d90cb7025
DOI: 10.1101/2022.11.10.515939

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