Article

Building a single cell transcriptome-based coordinate system for cell ID with SURE

2024-11-15

Abstract excerpt

The growing scale of single cell data demands standardized cell identification. We develop SURE, a data-driven method that establishes a cell coordinate system through optimally-sized metacells exhibiting enhanced transcriptional homogeneity. This approach enables precise cellular state characterization while providing three key atlas functionalities: zero-shot query-to-reference mapping, out-of-atlas detection, a...

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Identifiers and source

Literature Corpus work: fbc66508-471e-59ef-bc0f-aba462960473
DOI: 10.1101/2024.11.13.623403

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