Article

Directional information flow as a tool for analyzing protein allostery

2026-06-23

Abstract excerpt

<h4>ABSTRACT</h4> The ability to tune protein function through the binding of modulatory ligands enables the development of therapeutics that steer a biological system away from dysfunctional states underlying disease. Understanding the dynamic mechanisms by which allosteric ligands alter protein function remains an important open question. Dynamical network models allow us to quantify information flow between pr...

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Literature Corpus work: 1e03cb22-3188-5506-b12e-c9fd31e72eee
DOI: 10.64898/2026.06.22.733418

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