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Active Gaussian Network Model: a non-equilibrium description of protein fluctuations and allosteric behavior

2025-05-30

Abstract excerpt

Understanding the link between structure and function in proteins is fundamental in molecular biology and proteomics. A central question in this context is whether allostery — where the binding of a molecule at one site affects the activity of a distant site — emerges as a further manifestation of the intricate interplay between structure, function, and intrinsic dynamics. This study explores how allosteric regula...

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Literature Corpus work
ed4bc0dd-5d65-54fd-84ae-4d84262d130c
DOI
10.1101/2025.05.28.656626
Open publication

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Active Gaussian Network Model: a non-equilibrium description of protein fluctuations and allosteric behaviorDOI 10.1101/2025.05.28.656626
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