Article

Analysis of allelic cross-reactivity of monoclonal IgG antibodies by a multiplexed reverse FluoroSpot assay

2022-04-29

Abstract excerpt

The issue of antibody cross-reactivity is of central importance in immunology, and not least in protective immunity to Plasmodium falciparum malaria, where key antigens show substantial allelic variation (polymorphism). However, serological analysis often does not allow the distinction between true cross-reactivity (one antibody recognizing multiple antigen variants) and apparent cross-reactivity (presence of mul...

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Literature Corpus work: 1de19bd2-70e0-5f29-97bb-e8ef495caeea
DOI: 10.1101/2022.04.28.489862

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