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Article

Association of MUC16 Mutation With Tumor Mutation Load and Outcomes in Patients With Gastric Cancer.

JAMA oncology - 1 Dec 2018

Li Xiangchun, Pasche Boris, Zhang Wei, Chen Kexin

Abstract excerpt

Importance: MUC16, which encodes cancer antigen 125 (CA-125), is frequently mutated in gastric cancer (GC); however, its association with tumor mutation load (TML) and outcome in patients with GC has not been established, to date. Objective: To investigate whether MUC16 mutations are associated with TML and prognosis in patients with GC. Design, Setting, and Participants: Statistical analysis of genomic data from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30098163
DOI: 10.1001/jamaoncol.2018.2805
PMCID: PMC6440715

Genes

MUC16
BRCA1
POLE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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