Article
p16 gene alterations in human ovarian cancers: comparison between tissue and blood samples.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 May 2012
Bammidi Lakshmi Sowjanya, Neerukonda Geetha Nagasree, Murthy Sudha, Kanapuram Rudrama Devi
Abstract excerpt
OBJECTIVE: To determine the alterations of tumor suppressor gene p16INK4A in human ovarian cancers to explore the possibilities of identifying potential minimally invasive markers in blood of the patients, which could help in the clinical practice as a diagnostic and prognostic marker. METHODS: Ovarian cancer tissue and corresponding blood samples were collected from patients (n = 50). The promoter methylation...
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