Article

Forty high-intensity interval training sessions blunt exercise-induced changes in the nuclear protein content of PGC-1α and p53 in human skeletal muscle

2019-03-17

Abstract excerpt

<h4>ABSTRACT</h4> Exercise-induced increases in peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and p53 protein content in the nucleus mediate the initial phase of exercise-induced mitochondrial biogenesis. Here we investigated if exercise-induced increases in these and other markers of mitochondrial biogenesis were altered after 40 sessions of twice-daily high-volume high-intensity interval...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1d9bcec1-657f-523e-81f6-f7601747dda6
DOI: 10.1101/580373

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Forty high-intensity interval training sessions blunt exercise-induced changes in the nuclear protein content of PGC-1α and p53 in human skeletal muscleDOI 10.1101/580373Read

High-Intensity Exercise and Mitochondrial Biogenesis: Current Controversies and Future Research DirectionsSemantic proximity Read

Training-induced bioenergetic improvement in human skeletal muscle is associated with non-stoichiometric changes in the mitochondrial proteome without reorganization of respiratory chain contentSemantic proximity Read

Normobaric hypoxia alters the transcriptional response of healthy human skeletal muscles to a single session of high-intensity interval exerciseSemantic proximity Read

The effects of aging, physical training, and a single bout of exercise on mitochondrial protein expression in human skeletal muscleSemantic proximity Read

p53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content.Semantic proximity Read

Calorie Restriction Increases Muscle Mitochondrial Biogenesis in Healthy HumansSemantic proximity Read

Repeated-ischaemic exercise enhances mitochondrial and ion transport gene adaptations in human skeletal muscle – Role of muscle redox state and AMPKSemantic proximity Read

Coordination of mitochondrial biogenesis by PGC-1α in human skeletal muscle: A re-evaluationSemantic proximity Read

Acute exercise induces tumour suppressor protein p53 translocation to the mitochondria and promotes a p53–Tfam–mitochondrial DNA complex in skeletal muscleSemantic proximity Read

Truncated splice variant PGC-1<i>α</i>4 is not associated with exercise-induced human muscle hypertrophySemantic proximity Read

A HIF-1 signature dominates the attenuation in the human skeletal muscle transcriptional response to high-intensity interval trainingSemantic proximity Read

PGC-1 isoforms and their target genes are expressed differently in human skeletal muscle following resistance and endurance exerciseSemantic proximity Read