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Article

A HIF-1 signature dominates the attenuation in the human skeletal muscle transcriptional response to high-intensity interval training

28 Apr 2022

Abstract excerpt

This is the first study to address the phenomena of attenuation of the acute exercise response on a global genomic scale with a focus on underlying regulatory machinery and it is, to the best of our knowledge, the first study conducted in humans was exercise-induced regulation of different canonical pathways and transcription factors are contrasted with regards to attenuation after a period with regular exercise...

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PMID: 35482326
DOI: 10.1152/japplphysiol.00310.2021

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