Article
Cell-type heterogeneity in adipose tissue is associated with complex traits and reveals disease-relevant cell-specific eQTLs
2018-03-18
Abstract excerpt
Adipose tissue is comprised of a heterogeneous collection of cell-types which can differentially impact disease phenotypes. We investigated cell-type heterogeneity in two population-level subcutaneous adipose tissue RNAseq datasets (TwinsUK, N =766 and GTEx, N=326). We find that adipose cell-type composition is heritable and confirm the positive association between macrophage proportion and obesity (BMI), but find...
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Identifiers and source
- Literature Corpus work
- 1d957338-8d95-5125-a284-e765ec4d2e83
- DOI
- 10.1101/283929