Article

Matrix stiffness regulates Notch signaling activity in endothelial cells

2022-04-20

Abstract excerpt

The Notch signaling pathway plays a critical role in many developmental and disease related processes. It is widely accepted that Notch has a mechano-transduction module that regulates cleavage of the receptor. However, the role of biomechanical properties of the cellular environment on this module and on Notch signaling in general is still poorly understood. During angiogenesis, differentiation into tip and stalk...

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Literature Corpus work: 1d8688e3-e492-5287-ab12-278892c1456f
DOI: 10.1101/2022.04.20.488899

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