Targeting Quorum Sensing in Pseudomonas Aeruginosa Biofilms: Current and Emerging Inhibitors

Abstract excerpt

Bacterial resistance to conventional antibiotics combined with an increasing acknowledgement of the role of biofilms in chronic infections has led to a growing interest in new antimicrobial strategies that target the biofilm mode of growth. In the aggregated biofilm mode, cell-to-cell communication systems involved in the process known as quorum sensing regulate coordinated expression of virulence with immune...

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