Article

Efficacy of a phage cocktail preparation for chronic lung infection with <i>Pseudomonas aeruginosa</i> in mice

2023-04-25

Abstract excerpt

Pseudomonas aeruginosa is a leading cause of hospital-acquired infections, and the emergence of multi-drug resistant strains has prompted the search for alternative treatments such as phage therapy. In this study, we combined host range and genomic information to design a four-phage cocktail that effectively killed several clinical strains (79%, 23/29) of P. aeruginosa . We demonstrated that the cocktail, compose...

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Literature Corpus work: 6357fd10-5955-530a-9865-0a15ab6de93f
DOI: 10.1101/2023.04.25.538306

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