Article

Defining muscle-invasive bladder cancer immunotypes by introducing tumor mutation burden, CD8+ T cells, and molecular subtypes

2020-12-11

Abstract excerpt

<title>Abstract</title> <p>Immunotherapy, especially anti-PD-1, is becoming a pillar of modern muscle-invasive bladder cancer (MIBC) treatment. However, the objective response rates (ORR) are relatively low due to the lack of precise biomarkers to select patients. Herein, the molecular subtype, tumor mutation burden (TMB), and CD8+ T cells were calculated by the gene expression and mutation profiles of MIBC patie...

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Literature Corpus work: f6a9b423-7f42-58b9-982b-901092a7352f
DOI: 10.21203/rs.3.rs-54624/v2

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