Article

Initiation site of experimentally-evoked spreading depolarizations influence tissue outcomes in a murine stroke model

2025-10-06

Abstract excerpt

Spreading depolarization waves (SDs) are implicated in secondary expansion of brain injuries and are the target for initial clinical intervention trials. However, the assumption that SD directly causes neuronal injury has been challenged by recent findings with experimentally-induced SD in stroke models. The current study addressed this controversy by examining whether stroke consequences are confounded by the pre...

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Literature Corpus work: 1d021a2f-7e35-5584-8030-02171d5a0423
DOI: 10.1101/2025.10.03.680372

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