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m <sup>6</sup> A mRNA Methylation in Brown Adipose Tissue Regulates Systemic Insulin Sensitivity via an Inter-Organ Prostaglandin Signaling Axis

2023-05-26

Abstract excerpt

<h4>Summary</h4> Brown adipose tissue (BAT) has the capacity to regulate systemic metabolism through the secretion of signaling lipids. N6-methyladenosine (m 6 A) is the most prevalent and abundant post-transcriptional mRNA modification and has been reported to regulate BAT adipogenesis and energy expenditure. In this study, we demonstrate that the absence of m 6 A methyltransferase-like 14 (METTL14), modifies...

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Literature Corpus work
1cdc6e5b-6c09-54ab-a2e0-a3106fd4e3cb
DOI
10.1101/2023.05.26.542169
Open publication

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m <sup>6</sup> A mRNA Methylation in Brown Adipose Tissue Regulates Systemic Insulin Sensitivity via an Inter-Organ Prostaglandin Signaling AxisDOI 10.1101/2023.05.26.542169
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