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Article

m6A Regulators in Human Adipose Tissue - Depot-Specificity and Correlation With Obesity.

Frontiers in endocrinology - 1 Jan 2021

Rønningen Torunn, Dahl Mai Britt, Valderhaug Tone Gretland, Cayir Akin, Keller Maria, Tönjes Anke, Blüher Matthias, Böttcher Yvonne

Abstract excerpt

Background: N6-methyladenosine (m6A) is one of the most abundant post-transcriptional modifications on mRNA influencing mRNA metabolism. There is emerging evidence for its implication in metabolic disease. No comprehensive analyses on gene expression of m6A regulators in human adipose tissue, especially in paired adipose tissue depots, and its correlation with clinical variables were reported so far. We...

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Identifiers

PMID: 34950106
DOI: 10.3389/fendo.2021.778875
PMCID: PMC8689137

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