Article

CWAS-Plus: Estimating category-wide association of rare noncoding variation from whole-genome sequencing data with cell-type-specific functional data

2024-04-15

Abstract excerpt

<h4>ABSTRACT</h4> Variants in cis-regulatory elements link the noncoding genome to human brain pathology; however, detailed analytic tools for understanding the association between cell-level brain pathology and noncoding variants are lacking. CWAS-Plus, adapted from a Python package for category-wide association testing (CWAS) employs both whole-genome sequencing and user-provided functional data to enhance nonco...

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Literature Corpus work: 1cb5771d-a5a7-58a5-8e99-db64fde016b3
DOI: 10.1101/2024.04.15.24305828

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