Article

Mass spectrometry based immunopeptidomics leads to robust predictions of phosphorylated HLA class I ligands

2019-11-09

Abstract excerpt

The presentation of peptides on class I human leukocyte antigen (HLA-I) molecules plays a central role in immune recognition of infected or malignant cells. In cancer, non-self HLA-I ligands can arise from many different alterations, including non-synonymous mutations, gene fusion, cancer-specific alternative mRNA splicing or aberrant post-translational modifications. Identifying HLA-I ligands remains a challengin...

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Literature Corpus work: 1c99768c-7d2d-53ed-bf0a-5ee6f6de757f
DOI: 10.1101/836189

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