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The Role of Mass Spectrometry and Proteogenomics in the Advancement of HLA Epitope Prediction

3 Jan 2018

Abstract excerpt

A challenge in developing personalized cancer immunotherapies is the prediction of putative cancer-specific antigens. Currently, predictive algorithms are used to infer binding of peptides to human leukocyte antigen (HLA) heterodimers to aid in the selection of putative epitope targets. One drawback of current epitope prediction algorithms is that they are trained on datasets containing biochemical HLA-peptide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29314742
DOI: 10.1002/pmic.201700259

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