Article

Unperturbed dormancy recording reveals stochastic awakening strategies in endocrine treated breast cancer cells

2021-04-22

Abstract excerpt

Hormone dependent breast cancer (HDBC) is the most commonly diagnosed tumor type in women. Adjuvant endocrine therapies (ET) have been the cornerstone in the clinical management of HDBC patients for over forty years. A vast proportion of HDBC patients incur long periods of clinical dormancy following ET, with tumour awakening appearing at a steady pace for up to 25 years (Pan et al., 2017). Extensive genomic studi...

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Literature Corpus work: 1c97cafc-e93c-5594-a8aa-a261fdc6923b
DOI: 10.1101/2021.04.21.440779

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