Article

Molecular changes during extended neoadjuvant letrozole treatment of breast cancer: distinguishing acquired resistance from dormant tumours

2018-09-25

Abstract excerpt

<h4>Background</h4> The risk of recurrence for endocrine-treated breast cancer patients persists for many years or even decades following surgery and apparently successful adjuvant therapy. This period of dormancy and acquired resistance is inherently difficult to investigate, previous efforts have been limited to in vitro or in vivo approaches. In this study, sequential tumour samples from patients receiving e...

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Literature Corpus work: befaff95-c018-5ba3-9f5e-76be91213b6b
DOI: 10.1101/426155

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