Article

T cell Aryl Hydrocarbon Receptor Activity Tunes the Gut Microenvironment to Sustain Autoimmunity and Neuroinflammation

2022-04-19

Abstract excerpt

Multiple sclerosis (MS) is a T cell driven autoimmune disease that attacks the myelin of the central nervous system and currently has no cure. MS etiology is linked to both the gut flora and external environmental factors but this connection is not well understood. One immune system regulator responsive to non-pathogenic external stimuli is the aryl hydrocarbon receptor (AHR). The AHR, which binds diverse molecule...

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Literature Corpus work: 1c79c9ef-96eb-5494-b935-43651792857b
DOI: 10.1101/2022.04.19.488821

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