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The aryl hydrocarbon receptor pathway: a linking bridge between the gut microbiome and neurodegenerative diseases

8 Aug 2024

Abstract excerpt

The Aryl hydrocarbon receptor (AHR) is a cytosolic receptor and ligand-activated transcription factor widely expressed across various cell types in the body. Its signaling is vital for host responses at barrier sites, regulating epithelial renewal, barrier integrity, and the activities of several types of immune cells. This makes AHR essential for various cellular responses during aging, especially those...

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PMID: 39175504
DOI: 10.3389/fncel.2024.1433747

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