Article

Bile acid supplementation improves murine pancreatitis in association with the gut microbiota

2020-02-14

Abstract excerpt

<h4>ABSTRACT</h4> Disorders of bile acids (BAs) are closely related to the development of liver and intestinal diseases, including acute pancreatitis (AP). However, the mechanism underlying the involvement of BAs in AP development remains unclear. We used intraperitoneal injection of cerulein to construct AP mouse models. These mice had significantly reduced tauroursodeoxycholic acid (TUDCA) and an imbalance of i...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1c42d7c4-e1d2-5610-856b-b80d86a6c6c2
DOI: 10.1101/2020.02.13.948547

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bile acid supplementation improves murine pancreatitis in association with the gut microbiotaDOI 10.1101/2020.02.13.948547Read

Targeting Bile-Acid Metabolism: Nutritional and Microbial Approaches to Alleviate Ulcerative ColitisSemantic proximity Read

Gut dysbiosis protects against liver injury in autophagy deficient mice by FXR-FGF15 feedback signalingSemantic proximity Read

Hepatic inflammation caused by dysregulated bile acid synthesis is reversible by butyrate supplementation.Semantic proximity Read

Microbiota metabolized Bile Acids accelerate Gastroesophageal Adenocarcinoma via FXR inhibitionSemantic proximity Read

The alterations of gut microbiota in mice with chronic pancreatitisSemantic proximity Read

The gut microbiota at the intersection of bile acids and intestinal carcinogenesis: An old story, yet mesmerizingSemantic proximity Read

Gut microbiota-derived bile acids in intestinal immunity, inflammation, and tumorigenesisSemantic proximity Read

Bile acid is a significant host factor shaping the gut microbiome of diet-induced obese miceSemantic proximity Read

Cross-talk between bile acids and intestinal microbiota in host metabolism and healthSemantic proximity Read

Novel Approaches in Glucose and Lipid Metabolism Disorder Therapy: Targeting the Gut Microbiota–Bile Acid AxisSemantic proximity Read

Secondary bile acid lithocholic acid ameliorates colitis-like inflammation in a human intestine-on-chip systemSemantic proximity Read

A Network Involving Gut Microbiota, Circulating Bile Acids, and Hepatic Metabolism Genes That Protects Against Non‐Alcoholic Fatty Liver DiseaseSemantic proximity Read