Article

Deeplearning based MHC epitope prediction for cancer neoantigen discovery

2021-11-13

Abstract excerpt

Neoantigens are important for cancer immunotherapies or cancer vaccine development, but identification of neoantigens is challenging. The high binding affinity between the mutated peptide and MHC (major histocompatibility complex) molecules of the patients is a necessary factor for a somatic mutation on the tumor genome to form a neoantigen. MHC epitope prediction tools can be used for the identification of neoant...

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Literature Corpus work: 1c4184ad-f45c-59fc-8bd5-788f60a3d5e1
DOI: 10.1101/2021.11.10.468160

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