Article

Blunted glucocorticoid responsiveness to stress causes behavioral and biological alterations that lead to posttraumatic stress disorder vulnerability

2023-08-21

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Understanding why only a subset of trauma-exposed individuals develop posttraumatic stress disorder (PTSD) is critical for advancing clinical strategies. A few behavioral (deficits in fear extinction) and biological (blunted glucocorticoid levels, small hippocampal size, and rapid-eye movement sleep (REMS) disturbances) traits have been identified as potential vulnerability...

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Literature Corpus work: 1c1c85cc-028c-59e4-a6ce-fa51c5392cbb
DOI: 10.1101/2023.08.20.554001

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