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Article

From Memory Impairment to Posttraumatic Stress Disorder-Like Phenotypes: The Critical Role of an Unpredictable Second Traumatic Experience.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 2 Dec 2015

Finsterwald Charles, Steinmetz Adam B, Travaglia Alessio, Alberini Cristina M

Abstract excerpt

Arousal and stress critically regulate memory formation and retention. Increasing levels of stress produce an inverted U-shaped effect on cognitive performance, including the retention of explicit memories, and experiencing a severe stress during a traumatic event may lead to posttraumatic stress disorder (PTSD). The molecular mechanisms underlying the impairing effect of a severe stress on memory and the key...

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Identifiers

PMID: 26631471
DOI: 10.1523/JNEUROSCI.0771-15.2015
PMCID: PMC4666915

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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