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A brief review on the Human Encyclopedia of DNA Elements (ENCODE) project.

Genomics, proteomics & bioinformatics - 1 Jun 2013

Qu Hongzhu, Fang Xiangdong

Abstract excerpt

The ENCyclopedia Of DNA Elements (ENCODE) project is an international research consortium that aims to identify all functional elements in the human genome sequence. The second phase of the project comprised 1640 datasets from 147 different cell types, yielding a set of 30 publications across several journals. These data revealed that 80.4% of the human genome displays some functionality in at least one cell...

Topics

Chromatin
DNA
DNA Methylation
Disease
Genetic Variation
Genome, Human
Genome-Wide Association Study
Humans
Molecular Sequence Annotation
National Human Genome Research Institute (U.S.)
Regulatory Sequences, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transcription, Genetic

United States

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Identifiers

PMID: 23722115
DOI: 10.1016/j.gpb.2013.05.001
PMCID: PMC4357814

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