Article

A dual-receptor model of serotonergic psychedelics

2024-04-15

Abstract excerpt

Serotonergic psychedelics have been identified as promising next-generation therapeutic agents in the treatment of mood and anxiety disorders. While their efficacy has been increasingly validated, the mechanism by which they exert a therapeutic effect is still debated. A popular theoretical account is that excessive 5-HT2a agonism disrupts cortical dynamics, relaxing the precision of maladaptive high-level beliefs...

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Literature Corpus work: fdd9b853-e279-5a5d-b43d-b778889fbb95
DOI: 10.1101/2024.04.12.589282

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