Article

Hierarchical classification of hematologic malignancies using epigenetic and genetic information

2026-07-03

Abstract excerpt

<h4>ABSTRACT</h4> Molecular testing in hematology requires different assays for disease subgroup identification, risk stratification and selection of appropriate treatment regimens. Yet, molecular tests are not necessarily standardized between diagnostic laboratories, resulting in varying turnaround times and potentially divergent results. To resolve this issue and enable single-assay molecular testing, we have d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1bbbcf3e-89e3-51ad-9f5c-d6b8520a9478
DOI: 10.64898/2026.07.02.735835

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hierarchical classification of hematologic malignancies using epigenetic and genetic informationDOI 10.64898/2026.07.02.735835Read

Epigenomic diagnosis and prognosis of Acute Myeloid LeukemiaSemantic proximity Read

Epigenomic insights and computational advances in hematologic malignanciesSemantic proximity Read

Network-based clustering unveils interconnected landscapes of genomic and clinical features across myeloid malignanciesSemantic proximity Read

Artificial Intelligence in cancer epigenomics: a review on advances in pan-cancer detection and precision medicineSemantic proximity Read

Comprehensive pan-cancer analysis of cfDNA methylation marks in tumors reveals complex epigenetic regulatory circuits and diagnostic biomarkersSemantic proximity Read

Knowledge-informed multimodal cfDNA analysis improves sensitivity and generalization in cancer detectionSemantic proximity Read

Sensitive and specific multi-cancer detection and localization using methylation signatures in cell-free DNASemantic proximity Read

TUCAN: Ultra-fast methylation-based classification of pediatric solid tumors and lymphomasSemantic proximity Read

Building a genetic and epigenetic predictive model of breast cancer intrinsic subtypes using large-scale data and hierarchical structure learningSemantic proximity Read

Comprehensive Genomic Profiling Reveals Diverse but Actionable Molecular Portfolios across Hematologic Malignancies: Implications for Next Generation Clinical TrialsSemantic proximity Read

Co-mapping clonal and transcriptional heterogeneity in somatic evolution via GoT-Multi.Semantic proximity Read

Diagnostic yield of exome reanalysis over time: Contribution of reevaluation type, timing, and patient phenotype.Semantic proximity Read