Article

Patient-Derived Free-Floating Non-Small Cell Lung Cancer Organoids: A Versatile Tool for Personalized Testing of Chemotherapeutic Drugs

2024-01-22

Abstract excerpt

Patient-derived tumor organoids (PDTOs) are a novel preclinical model of non-small cell lung cancer (NSCLC) for studying tumor biology and precision medicine, which recapitulates tumor morphology and gene expression profile. However, some issues such as low establishment rates, long-term production, and the loss of the immune microenvironment have hindered their widespread practical use. In this study, we investig...

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Literature Corpus work: 1bb9bff7-f7f2-5481-b73a-757778a98e60
DOI: 10.20944/preprints202312.2280.v2

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