Article

Chromatin regulatory dynamics of early human small intestinal development using a directed differentiation model

2019-12-19

Abstract excerpt

<h4>Background</h4> The establishment of the small intestinal (SI) lineage during human embryogenesis is critical for the proper development of neonatal gut functions, including nutrient absorption and immune defense. The chromatin dynamics and regulatory networks that drive human SI lineage formation and regional patterning are essentially unknown. To fill this knowledge void, we apply a cutting-edge genomic tec...

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Literature Corpus work: 1b729447-d688-5823-86e7-43e53c80553d
DOI: 10.1101/2019.12.18.881219

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