Article

DeepPHiC: Predicting promoter-centered chromatin interactions using a novel deep learning approach

2022-05-25

Abstract excerpt

<h4>Motivation</h4> Promoter-centered chromatin interactions, which include promoter-enhancer and promoter-promoter interactions, are important to decipher gene regulation and disease mechanisms. The development of next generation sequencing technologies such as promoter capture Hi-C (pcHi-C) leads to the discovery of promoter-centered chromatin interactions. However, pcHi-C experiments are expensive and thus may...

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Literature Corpus work: 1a9c9040-f5e6-5447-9456-6a2f5f09dfba
DOI: 10.1101/2022.05.24.493333

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