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Ancient implications for today’s precision medicine: How the first Near East farmers shaped the European genetic risk architecture for IBD

2022-09-28

Abstract excerpt

<title>Abstract</title> <p>Inflammatory bowel disease (IBD) is often described as a model for modern civilization diseases in which environmental factors trigger disease manifestation in genetically compromised individuals. Little is known about the evolutionary history of variants associated with IBD in modern Europeans. Here, we analysed 610 IBD-variants in 2445 ancient datasets from human remains spanning the...

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Literature Corpus work: 1a607c09-4645-5b86-860a-1cec74fd9c66
DOI: 10.21203/rs.3.rs-2075746/v1

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